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The Thursday MLB schedule features 11 games and while there are some enticing matchups, every one offers numerous players to choose for your best bet to hit a home run wager at the best sports betting apps . One of the highlights of the day is White Sox vs. Red Sox as Boston goes for a three-game sweep and an eighth straight victory. The final game of a Padres vs. Diamondbacks four-game set also has some intrigue as the NL West foes battle for a wild card spot while the Dodgers run away with the division. SportsLine expert Adam Thompson has scoured all the odds for Thursday's games and provides his best home run player props for the slate here.
Thompson was one of SportsLine's earliest experts from 2016-19 and rejoined the company in 2026 following a stint as the primary betting analyst for the Gambling.com Group. An analytics-driven exploiter of matchups, Thompson specializes in NFL , MLB and NBA . He also has delivered consistent winners in college basketball, horse racing and golf. Over the past two seasons, he's up over 70 units in MLB and more than 60 units in the NBA at sports betting sites .
Here are Thompson's home run picks for Thursday, Aug. 6.
Someone's hitting a home run for the Phillies. Nationals starter Miles Mikolas has allowed 16 homers in 10 starts and 26 overall. He's allowed six of them over his past three starts.
Harper could be that guy. He has only one home run in 24 at bats vs. Mikolas, but a .333 average and .902 OPS suggest he's hit well. After hitting home runs on Sunday and Monday, Harper was walked twice on Tuesday and Wednesday. Mikolas has issued six walks in his past 10 games combined. He's up there to throw strikes, meaning Harper will get some chances to go yard.
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Luis Castillo makes his White Sox debut after being traded from the Mariners . He goes from a pitcher-friendly park to one more down the middle, but favorable toward left-handed hitters.
Yoshida has yet to homer off Castillo, but he is 5-for-8 lifetime against the pitcher. Castillo allowed only four home runs in Seattle, but 12 in 10 road starts. The left-handed Yoshida has only five home runs, but they're all against right-handed pitchers. He's worth backing in a matchup he likes in a ballpark that likes him.
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